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Free Content Sensitivity and specificity of BCG scar reading in Brazil

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Abstract:

In a cross sectional survey within a community trial of BCG efficacy evaluation in Brazil, trained teams inspected childrenÕs upper arms and obtained information on BCG vaccination from guardian letters and vaccination cards. Nurses re-examined the sub-sample of children blindly. High agreement was found between the two scar readings (Kappa = 0.839). High sensitivity and low specificity was observed when guardian or card information was the gold standard. Sensitivity remained high when guardian and card information agreed. When disagreement occurred, sensitivity remained high and specificity was very low. BCG scar is a good indicator of BCG vaccination.

Keywords: BCG scar; BCG vaccine; sensitivity; specificity; validation

Document Type: Short Communication

Affiliations: 1: Instituto de Saúde Coletiva, Salvador, Bahia, Brazil 2: Infectious Disease and Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, England 3: Coordenação Regional da Fundação Nacional de Saúde, Salvador, Bahia, Brazil 4: Centro de Referência Hélio Fraga/Cenepi/FUNASA, Rio de Janeiro, Brazil

Publication date: 2001-11-01

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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