Atypical radiological images of pulmonary tuberculosis in 192 diabetic patients: a comparative study
Authors: Pérez-Guzmán C.1; Torres-Cruz A.2; Villarreal-Velarde H.3; Salazar-Lezama M. A.2; Vargas M. H.4
Source: The International Journal of Tuberculosis and Lung Disease, Volume 5, Number 5, May 2001 , pp. 455-461(7)
Publisher: International Union Against Tuberculosis and Lung Disease
Abstract:
SETTING: Comparative studies of pulmonary tuberculosis images in diabetics have yielded conflicting results.
OBJECTIVE: To assess radiological images of pulmonary tuberculosis in a large population of diabetic patients
DESIGN: Radiographs from in-patients admitted with pulmonary tuberculosis and diabetes (TBDM group, n = 192) were reviewed and compared with a control group of patients with pulmonary tuberculosis alone (TB group, n = 130).
RESULTS: Both groups had a similar evolution time of tuberculosis (
2 years). Statistical differences were observed as follows: TBDM patients were older (51.3 ± 0.9 vs. TB group 44.9 ± 1.8 years, mean ± SEM), and had a decreased frequency of upper (17% vs. 56%), and an increased frequency of lower (19% vs. 7%) and upper + lower (64% vs. 36%) lung field lesions. More TBDM patients developed cavitations (82% vs. 59%) more often in the lower lung fields (29% vs. 3%). More multiple cavities were seen in TBDM patients (25% vs. 2%). TBDM group had a lower total leukocyte count (8836.7 ± 219.5 vs. 10013.1 ± 345.2 cells/mm3), mainly due to a lower number of non-lymphocyte cells (6815.8 ± 221.8 vs. 8095.7 ± 321.9 cells/mm3). Multiple logistic regression showed that being a diabetic patient was the most important factor determining lower lung field lesions and cavities.
CONCLUSIONS: This study in a large number of diabetics with pulmonary tuberculosis confirmed that their chest X-ray images significantly depart from the typical presentation. Clinicians must keep this in mind to avoid misdiagnosis.
Keywords: cavitation; chest X-rays; comparative study; diabetes mellitus; pulmonary tuberculosis; radiology; roentgenogram
Language: English
Document Type: Regular paper
Affiliations: 1: Instituto Nacional de Enfermedades Respiratorias, Departamento de Neumología, Hospital General, CMN La Raza, Instituto Mexicano del Seguro Social, México DF, México 2: Instituto Nacional de Enfermedades Respiratorias, México DF, México 3: Hospital General ?Dr. Manuel Gea González?, México DF, México 4: Instituto Nacional de Enfermedades Respiratorias, and Hospital de Pediatría, CMN Siglo XXI, Instituto Mexicano del Seguro Social, México DF, México
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