Free Content IS1607, a single-copy insertion sequence-related element of the Mycobacterium tuberculosis complex [Technical Note]

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The species specificity of IS1607, a new Mycobacterium tuberculosis complex insertion sequence-related element, was investigated. IS1607 was present as a single copy in M. tuberculosis, M. bovis and M. bovis BCG strains. This sequence also existed in M. africanum and M. microti, but was not present in 69 strains of 19 atypical mycobacterial species analyzed by using polymerase chain reaction (PCR) or Southern hybridization assay. IS1607 appears to be specific for the M. tuberculosis complex.

Keywords: IS1607; Mycobacterium tuberculosis complex; PCR

Document Type: Short Communication

Affiliations: 1: Centre for Microbiology and Virology, Polish Academy of Sciences, Lódz, Poland 2: Department of Genetics of Microorganisms, University of Lódz, Lódz, Poland 3: School of Biological Sciences, University of Surrey, Guildford, UK

Publication date: November 1, 2000

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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