Trials of anti-tuberculosis treatment in areas of high human immunodeficiency virus prevalence in sub-Saharan Africa [Unresolved Issues]
Abstract:Sub-Saharan Africa is bearing the brunt of the human immunodeficiency virus (HIV) pandemic, and HIV-associated tuberculosis (TB) has become a major clinical and public health problem. There is evidence that HIV-infected patients not uncommonly develop disseminated TB, and that this diagnosis is often not made ante mortem because of limited diagnostic facilities and other factors. Where diagnostic facilities are limited, a trial of anti-tuberculosis treatment with drugs specific for Mycobacterium tuberculosis may be a useful way of diagnosing disseminated TB. The case for and against ‘a trial of treatment’ is presented, and a suggestion is made that ‘a trial of treatment’ can be incorporated into the case finding package of a National TB Control Programme.
Document Type: Miscellaneous
Affiliations: 1: National Tuberculosis Control Programme, Ministry of Health, Capital City, Lilongwe, Malawi 2: National Tuberculosis Control Programme, Ministry of Health, Capital City, Lilongwe, Malawi; and Liverpool School of Tropical Medicine, Liverpool, UK 3: National Tuberculosis Control Programme, Ministry of Health, Capital City, Lilongwe, Malawi; and Department of Medicine, College of Medicine, Blantyre, Malawi
Publication date: November 1, 2000
The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.
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