Association of prevalence of tuberculin reactions with closeness of contact among household contacts of new smear-positive pulmonary tuberculosis patients [Notes from the Field]
Abstract:OBJECTIVES: Among household contacts of newly diagnosed smear-positive pulmonary tuberculosis (TB) patients, to examine the association of apparent tuberculosis transmission with the closeness and duration of contact.
METHODS: Household contacts of newly diagnosed patients with smear-positive pulmonary TB were identified, as well as a healthy population sample. Household contacts were categorized into three groups based on closeness, regularity, and duration of contact with index cases. All subjects underwent tuberculin testing.
RESULTS: Among the household contacts, 47 of 112 (42%) of very close/intimate contacts had positive tuberculin tests, compared to 121 of 356 (34%) close/regular contacts and 23 of 178 (13%) not close/sporadic contacts and 55 of 355 (16%) of a healthy population sample.
CONCLUSIONS: Even among household contacts of smear-positive pulmonary TB patients, there were major differences in the proximity and duration of contact which were strongly associated with differences in the prevalence of positive tuberculin reactions.
Document Type: Short Communication
Affiliations: 1: Jiyang Research Institute of Tuberculosis Control, Shandong Medical University, Jinan, Shandong, China 2: Department of Histology and Embryology, Shandong Medical University, Jinan, Shandong, China
Publication date: March 1, 2000
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