Treatment costs of directly observed therapy and traditional therapy for Mycobacterium tuberculosis: a comparative analysis
DESIGN: A retrospective economic evaluation of 659 tuberculosis cases was reported to a major metropolitan county public health department between 1980 and 1994. Out-patient costs, in-patient costs and the cost impact of relapse and acquired resistance were estimated in 1995 dollars.
RESULTS: Treatment costs were lower with DOT: $15670 per case for in-patient care and $700 per case for out-patient care (P < 0.001). These cost differences resulted from shorter therapy duration (334 vs 550 days), fewer patient hospitalizations (58 vs 75%) and shorter hospital stays (26 vs 55 days per hospitalized patient). Relapse or acquired resistance occurred in 10.9% of patients and accounted for 35.7% of cost with traditional therapy, as compared to 1.2% of patients and 6.0% of cost with observed therapy.
CONCLUSIONS: Directly observed therapy is less costly than traditional therapy.
Document Type: Regular Paper
Affiliations: 1: University of North Texas Health Science Center at Fort Worth, Forth Worth, Texas, USA; and Texas Department of Health, Austin, Texas, USA 2: University of North Texas Health Science Center at Fort Worth, Forth Worth, Texas, USA; and Division of Pulmonary, Allergy, Critical Care and Occupational Medicine, Indiana University School of Medicine, Texas, USA 3: University of North Texas Health Science Center at Fort Worth, Forth Worth, Texas, USA 4: Tarrant County Public Health Department, Texas, USA
Publication date: 1999-11-01
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