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Free Content Drug resistant tuberculosis in Estonia

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Setting: The incidence of drug resistant tuberculosis in Estonia has increased rapidly during the last five to six years.

Objective: To investigate the drug resistance patterns of Mycobacterium tuberculosis isolated from tuberculosis patients in Estonia.

Results: In 1994, 623 cases of tuberculosis were diagnosed in Estonia, 518 new cases with no previous history of tuberculosis, and 105 with a history of previous treatment for tuberculosis. All pulmonary M. tuberculosis isolates from 1994 were analysed for drug susceptibility. Of the 302 new cases (58.3%) that were culture verified, 28% had isolates resistant to one or more of the four drugs tested (isoniazid, rifampicin, streptomycin, ethambutol), and 9% had multi-drug resistant (resistant to at least isoniazid and rifampicin) strains.

Conclusion: The incidence of drug resistance in M. tuberculosis is high in Estonia.

Keywords: Estonia; drug resistance; tuberculosis

Document Type: Regular Paper

Affiliations: 1: Tartu University Lung Hospital, Tartu, Estonia 2: Kivimae Hospital, Tallinn, Estonia 3: Department of Bacteriology, Biomedicum, Swedish University for Agricultural Sciences, Uppsala, Sweden 4: Swedish Institute for Infectious Disease Control, Stockholm, Sweden

Publication date: 1998-02-01

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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