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Digital Printing of Bioinks

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Abstract:

Recently piezo-based ink jet printers have proven to be reliable, productive manufacturing tools particularly where expensive materials are involved. As bioengineers, we are capitalizing on the ability of piezoelectric-based drop-on-demand ink jets printers to precisely deposit a wide variety of biologically active materials to create custom arrayed libraries and patterns. These applications and many others take advantage of ink jet strengths as an additive, non-contact process. We have developed disposable ink jet cartridges and a laboratory bench-top printing system. We have printed many biological materials, and optimization of ink compositions has been the focus of our research. At this conference, we will discuss both solvent-based and aqueous bioinks. We will show the spatial deposition of both nanoinks and microinks and show the resulting biomaterial designs and arrays including DNA, bacteria, proteins and carbon nanotubes. We have printed gold nanoparticles and protein-bound nanospheres to allow patterning of fluorescent proteins. We will discuss ink composition and printing characteristics of these materials. Finally we will discuss wave form parameters for printing a broad range of aqueous materials used in the biosciences and performance characteristics during printing.

Document Type: Research Article

Publication date: January 1, 2006

More about this publication?
  • For more than 25 years, NIP has been the leading forum for discussion of advances and new directions in non-impact and digital printing technologies. A comprehensive, industry-wide conference, this meeting includes all aspects of the hardware, materials, software, images, and applications associated with digital printing systems, including drop-on-demand ink jet, wide format ink jet, desktop and continuous ink jet, toner-based electrophotographic printers, production digital printing systems, and thermal printing systems, as well as the engineering capability, optimization, and science involved in these fields.

    Since 2005, NIP has been held in conjunction with the Digital Fabrication Conference.

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