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Spectral Imaging of the Human Retina and Computationally Determined Optimal Illuminants for Diabetic Retinopathy Lesion Detection

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Abstract:

An ophthalmic fundus camera was modified for spectral imaging of the human retina. Spectral channels were separated using 30 narrow bandpass interference filters in the visual range from 400 to 700 nm. A monochrome digital charge-coupled device camera was used as a detector. Using this system, spectral fundus images were recorded from 72 voluntary human subjects: 55 diabetic patients and 17 healthy control subjects. Furthermore, using the gathered spectral data, optimal illuminations' spectral power distributions for the detection of different lesions of diabetic retinopathy and retinal landmarks (e.g., macula) were calculated. Optimized illuminations were found to enhance the visibility and contrast of retinal features. Computational example images are presented.

Document Type: Research Article

DOI: http://dx.doi.org/10.2352/J.ImagingSci.Technol.2011.55.3.030509

Affiliations: 1: InFotonics Center Joensuu, University of Eastern Finland, Joensuu Campus, Yliopistokatu 2, P.O. Box 111, FI-80101 Joensuu, Finland 2: Department of Ophthalmology, Kuopio University Hospital and University of Eastern Finland, Kuopio Campus, Yliopistonranta 1, P.O. Box 1627, FI-70211 Kuopio, Finland 3: Mehiläinen Eye Surgery Clinic, Itäinenkatu 3, FI-33210 Tampere, Finland 4: Department of Ophthalmology, Tampere University Hospital and University of Tampere, Kalevantie 4, FI-33014 University of Tampere, Finland

Publication date: May 1, 2011

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  • The Journal of Imaging Science and Technology (JIST) is dedicated to the advancement of imaging science knowledge, the practical applications of such knowledge, and how imaging science relates to other fields of study. The pages of this journal are open to reports of new theoretical or experimental results, and to comprehensive reviews. Only original manuscripts that have not been previously published, nor currently submitted for publication elsewhere, should be submitted.

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