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Sub-Pixel Retinal Vessel Tracking and Measurement Using Modified Canny Edge Detection Method

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This article presents a new method to track and measure retinal blood vessel with sub-pixel accuracy. The method is based on a modified Canny edge detection method and a Gaussian model of the vessel profile and zero cross of second order derivative of the Gaussian model. In this method, Canny edge detection method is used at first to detect edges from an input retinal image. The edge orientation is then refined and used to obtain vessel cross-sectional profile. Vessel sample profile is searched using local maximum and local minimum from the smoothed vessel cross-sectional profile. Gaussian model is then used to fit the vessel sample profile. The zeros cross of the second order derivatives of the Gaussian fit vessel sample profile are then used to represent the boundaries of the blood vessels. The peaks of the Gaussian fits are then used as positions of vessel center lines and to calculate the widths of the vessel at those points. The method outputs vessel wall positions, the center lines of the vessels with the widths of the vessels with respect to center points in sub-pixel accuracy.

Document Type: Research Article


Affiliations: School of Electrical and Electronics Engineering, Chung-Ang University, Seoul 156-756, South Korea

Publication date: 2008-03-01

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  • The Journal of Imaging Science and Technology (JIST) is dedicated to the advancement of imaging science knowledge, the practical applications of such knowledge, and how imaging science relates to other fields of study. The pages of this journal are open to reports of new theoretical or experimental results, and to comprehensive reviews. Only original manuscripts that have not been previously published, nor currently submitted for publication elsewhere, should be submitted.

    IS&T's JIST-first publication option allows authors wishing to present their work at conferences, but have a journal citation for their paper, to submit a paper to JIST that follows the same rigorous peer-review vetting and publication process as traditional JIST articles, but with the benefit of a condensed time-to-publication time frame and guaranteed conference presentation slot.

    Please note: For purposes of its Digital Library content, IS&T defines Open Access as papers that will be downloadable in their entirety for free in perpetuity. Copyright restrictions on papers vary; see individual paper for details.

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