Authors: Menon, Aditya¹; Krishnan, Chirakkal V.²; Nair, Cherupally Krishnan Krishnan³

Source: International Journal of Low Radiation, Volume 6, Number 3, 11 October 2009 , pp. 248-262(15)

Publisher: Inderscience Publishers

Abstract:

Whole-body exposure to gamma radiation was found to result in damage to cellular DNA and lowering of antioxidant levels in various tissues. Administration of POLY-MVA, a palladium-lipoic acid formulation, for seven days prior to whole body gamma radiation significantly reduced the damage to cellular DNA in bone marrow and blood leukocytes, as well as preventing the radiation-induced lowering of tissue antioxidant levels.

Keywords: ENVIRONMENTAL JOURNALS; Environment and Sustainable Development; HEALTHCARE AND LEISURE JOURNALS; Healthcare and Medical Engineering; ENVIRONMENTAL JOURNALS; Nuclear Science and Technology

Document Type: Research article

DOI: http://dx.doi.org/10.1504/IJLR.2009.028892

Affiliations: 1: Amala Cancer Research Centre, Thrissur 680555, Kerala, India. 2: Garnet McKeen Laboratory Inc., Bohemia, NY 11716-1735, USA; Department of Chemistry, University at Stony Brook, NY 11794-3400, USA. 3: Amala Cancer Research Centre, Thrissur 680555, Kerala, India

Publication date: 2009-10-11

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• The International Journal of Low Radiation is a peer-reviewed journal dedicated to the publication of research articles, review papers and technical notes in all domains related to low-dose radiation, among which are the biological and health effects in humans and the biota, in vitro and in vivo research on low radiation effects, regulatory and policy aspects, risk estimation and public perception.
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