Do Soy Isoflavones Cause Endometrial Hyperplasia?

Author: Mahady, Gail B.

Source: Nutrition Reviews, Volume 63, Number 11, November 2005 , pp. 392-397(6)

Publisher: International Life Sciences Institute

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Abstract:

For many years, hormone replacement therapy (HRT) was considered the gold standard for the symptomatic treatment of menopause. Clinical trials have found that HRT reduces the symptoms of hot flashes and sweating, while also decreasing vaginal dryness and urinary tract infections. HRT has also been shown to be protective against colon cancer (37%) and hip fractures (34%). However, recent findings from the Women's Health Initiative (WHI) have revealed that long-term HRT may actually lead to an increase in heart disease (29%), breast cancer (26%) and other adverse events, such as stroke (41%). Consequently, many women in the United States and abroad are actively looking for alternative treatments for menopause, including botanical dietary supplements.

Keywords: ENDOMETRIAL HYPERPLASIA; ISOFLAVONES; MENOPAUSE; SOY

Document Type: Review article

DOI: http://dx.doi.org/10.1301/nr.2005.nov.392-397

Publication date: 2005-11-01

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