Emerging Evidence on the Role of Soy in Reducing Prostate Cancer Risk

Author: Messina, Mark J.

Source: Nutrition Reviews, Volume 61, Number 4, 1 April 2003 , pp. 117-131(15)

Publisher: International Life Sciences Institute

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Abstract:

Soyfoods are a unique dietary source of isoflavones, which have both hormonal and non-hormonal effects relevant to prostate cancer prevention. In vitro, the main soybean isoflavone, genistein, inhibits prostate cancer cell growth; in animals, most but not all studies show isoflavone-rich soy protein and isolated isoflavones inhibit prostate tumor development. Currently, although only limited epidemiologic data indicate soy intake reduces prostate cancer risk, results from a pilot intervention trial suggest isoflavones may be beneficial to prostate cancer patients. For several reasons, men concerned about their prostate health may consider incorporating soy into their diet.

Keywords: SOY; ISOFLAVONES; GENISTEIN; PROSTATE; CANCER; REVIEW

Document Type: Review article

DOI: http://dx.doi.org/10.1301/nr.2003.apr.117-131

Publication date: 2003-04-01

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