Review of the Characteristics of Food-Derived and Endogenous N ε-Carboxymethyllysine

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Abstract:

N e-Carboxymethyllysine (CML), a representative of advanced glycation end products (AGEs), is commonly found in food and is considered a potential hazard to human health. Food scientists have begun to investigate the formation of CML in food processes. As the understanding of CML is mainly based on that of endogenous CML from the fields of biology and medicine, this review summarizes the different characteristics of food-derived CML and endogenous CML with respect to food safety, detection methods, formation environment, formation mechanism, and methods for inhibiting the formation of CML. Additionally, future research directions for the study of food-derived CML are proposed, including understanding its digestion, absorption, and metabolism in human health, developing rapid, reliable, and inexpensive detection methods, revealing its relationship with food components and production processes, and controlling the formation of CML through the addition of inhibitors and/or modification of food processing conditions, so as to contribute to the methods for controlling food-derived AGEs.

Document Type: Review Article

DOI: http://dx.doi.org/10.4315/0362-028X.JFP-12-472

Affiliations: 1: College of Light Industry and Food Sciences, South China University of Technology, 381 Wushan Road, Tianhe District, Guangzhou, China 510640 2: College of Light Industry and Food Sciences, South China University of Technology, 381 Wushan Road, Tianhe District, Guangzhou, China 510640. lcbingli@scut.edu.cn

Publication date: May 1, 2013

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    The Journal of Food Protection (JFP) is a refereed monthly publication. Each issue contains scientific research and authoritative review articles reporting on a variety of topics in food science pertaining to food safety and quality. The Journal is internationally recognized as the leading publication in the field of food microbiology with a readership exceeding 11,000 scientists from 70 countries. The Journal of Food Protection is indexed in Index Medicus, Current Contents, BIOSIS, PubMed, Medline, and many others.

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