Detection of 2-Alkylcyclobutanones, Markers for Irradiated Foods, in Adipose Tissues of Animals Fed with These Substances
Source: Journal of Food Protection®, Number 10, October 2002, pp. 1527-1673 , pp. 1610-1613(4)
Abstract:Laboratory rats received a freshly prepared drinking fluid containing 0.005% 2-tetradecyl- or 2-tetradecenyl-cyclobutanones daily for 4 months. These two compounds were recovered in the adipose tissues of the animals that consumed them. Less than 1% of the 2-alkylcyclobutanones ingested daily were excreted in the feces. In addition, our data indicate that 2-alkylcyclobutanones are able to cross the intestinal barrier, to enter into the bloodstream, and to be stored in the adipose tissue of an animal. However, the amounts of these substances detected in the adipose tissues and in the feces were much smaller than the amounts ingested.
Document Type: Research Article
Affiliations: 1: Laboratoire de Chimie Analytique et Sciences de l'Aliment (UMR 7512), Faculté de Pharmacie, Université Louis Pasteur, 74, route du Rhin, F-67400 Illkirch, France 2: Laboratoire de Prévention Nutritionnelle des Cancers (Inserm U392), Place de l'hôpital, F-67000 Strasbourg, France 3: Laboratoire de Chimie Organique Synthétique (UMR 7123), Faculté de Chimie, Université Louis Pasteur, 1, rue Blaise Pascal, F-67000 Strasbourg, France, 4: Groupe d'Epidémiologie Moléculaire du Cancer (UPR 9003), 1, Place de l'hôpital, F-67000 Strasbourg, France 5: Bundesforschungsanstalt für Ernährung, Haid-und-Neu-Strasse 9, D-76131 Karlsruhe, Germany 6: Institut für Lebensmittelchemie und Toxikologie, Universität Karlsruhe, Kaiserstrasse 12, D-76128 Karlsruhe, Germany 7: Aérial, 19 rue de Saint Junien, F-67300 Schiltigheim, France
Publication date: October 1, 2002
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