Skip to main content

Inhibition of Salmonella enteritidis Cecal and Organ Colonization in Leghorn Chicks by a Defined Culture of Cecal Bacteria and Dietary Lactose

Buy Article:

$37.00 plus tax (Refund Policy)


The effect of oral inoculation with a defined culture of cecal bacteria and provision of dietary lactose on colonization resistance to invasive Salmonella enteritidis was evaluated in leghorn chicks. A defined mixed culture composed of 11 indigenous cecal bacteria capable of utilizing lactose or lactose fermentation products as a primary carbon source was isolated and maintained in continuous-flow culture. Combined treatment with the defined culture and dietary lactose significantly decreased (P < 0.01) the number of Salmonella in the cecal contents and the number of Salmonella cecal-culture-positive chicks in four replicated trials. Additionally, Salmonella colonization of the spleen, liver, and cecal tonsils was significantly decreased (P < 0.05) in each of the trials. The results indicate that the resistance of leghorn chicks to S. enteritidis cecal and organ colonization is effectively increased by inoculation with a defined culture of cecal bacteria and provision of lactose in the diet.

Document Type: Research Article

Affiliations: 1: Agricultural Research Service, Food Animal Protection Research Laboratory, U.S. Department of Agriculture, Route 5, Box 810, College Station, Texas 77845 2: Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station, Texas 77843

Publication date: May 1, 1994

More about this publication?
  • IAFP Members with personal subscriptions to JFP Online: To access full-text JFP or JMFT articles, you must sign-in in the upper-right corner using your Ingenta sign-in details (your IAFP Member Login does not apply to this website).

    The Journal of Food Protection (JFP) is a refereed monthly publication. Each issue contains scientific research and authoritative review articles reporting on a variety of topics in food science pertaining to food safety and quality. The Journal is internationally recognized as the leading publication in the field of food microbiology with a readership exceeding 11,000 scientists from 70 countries. The Journal of Food Protection is indexed in Index Medicus, Current Contents, BIOSIS, PubMed, Medline, and many others.

    Print and online subscriptions are available to IAFP Members and institutional subscribers. IAFP Members with a subscription to JFP Online will have access to all available JFP and JMFT content. Online visitors who are not IAFP Members or journal subscribers will be charged on a pay-per-view basis. Membership and subscription information is available at
  • Information for Authors
  • Submit a Paper
  • Subscribe to this Title
  • Membership Information
  • Information for Advertisers
  • Ingenta Connect is not responsible for the content or availability of external websites

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Partial Open Access Content
Partial Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more