Metastatic Choriocarcinoma in a Middle-Aged Man Presenting as a Right Thigh Mass with Venous Thrombosis: A Case Report

Authors: Ilya Blokh; Stanley J. Oiseth; Joachim Fuks; Dharamuir Jain; Saji Eapen; Lydia Koulova; Doru Alexandrescu; Yuan-Yi Li; Janice Dutcher; Peter H. Wiernik

Source: Medical Oncology, Volume 20, Number 2, June 2003 , pp. 189-194(6)

Publisher: Humana Press

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Abstract:

Choriocarcinoma is a highly aggressive beta

-subunit of human chorionic gonadotropin ( beta

HCG)-producing germ cell tumor. In men, it is a rare neoplasm and can arise in the testes or in various extragonadal locations such as the retroperitoneum, mediastinum, and pineal body. We present a highly unusual case of a middle-aged man with primary metastatic beta

HCG-producing choriocarcinoma of the right thigh along with right lowerextremity venous thrombosis. We comment on prognostic variables as well as discuss several theories to account for the unusual location of his choriocarcinoma.

Keywords: Choriocarcinoma; beta-subunit of human chorionic gonadotropin; extragonadal choriocarcinoma

Document Type: Miscellaneous

Publication date: 2003-06-01