Choriocarcinoma of the Gallbladder: Treated with Cisplatin-Based Chemotherapy

In this: publication
By this: publisher
In this Subject: Oncology
By this author: Wang J.C. ;&nbsp; Angeles S. ;&nbsp; Chak P. ;&nbsp; Platt A.B. ;&nbsp; Nimmagadda N.

Authors: Wang J.C.; Angeles S.; Chak P.; Platt A.B.; Nimmagadda N.

Source: Medical Oncology, Volume 18, Number 2, March 2001 , pp. 165-169(5)

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Abstract:

A case of non-gestational choriocarcinoma, primary in the gallbladder, is described. Pathology showed a mixture of adenocarcinoma and choriocarcinoma. A Medline search for the last 10 years has shown no similar cases reported. The use of cisplatin-based chemotherapy to treat non-gestational choriocarcinoma has also not been described. This patient showed a rapidly progressive disease as described in other reported cases of non-gestational choriocarcinoma. However, cisplatin-based chemotherapy, in this patient, produced a partial response defined as significantly decreased beta -HCG titers (more than 50%), and with stable appearance or slightly improvement of hepatic metastasis and survival for 1 yr.