@article {P.:May 2003:1073-6085:259, author = "P. Norsworthy", author = "K. A. Davies", title = "Complement Components and Their Autoantibodies", journal = "Molecular Biotechnology", volume = "23", year = "May 2003", abstract = "The purpose of the immune system is to defend the host from constantly changing microbial pathogens. Autoimmune diseases develop as a consequence of the production of antibodies and/or cells that react with self-antigens, and may recruit other effector mechanisms that result in tissue damage. Thus, in this context, autoimmunity represents an immune response to self-antigens that is sufficient to cause disease. This article is specifically devoted to autoantibodies directed against complement components.", pages = "259-270(12)", url = "http://www.ingentaconnect.com/content/hum/mb/2003/00000023/00000003/art00006" }