Back to the Future: Antibody-Based Strategies for the Treatment of Infectious Diseases

Authors: Oral H.B.; Özakin C.; Akdi scedil C.A.

Source: Molecular Biotechnology, Volume 21, Number 3, July 2002 , pp. 225-240(16)

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Abstract:

Before antibiotics, sera from immune animals and humans were used to treat a variety of infectious diseases, often with successful results. After the discovery of antimicrobial agents, serum therapy for bacterial infections was rapidly forsaken. In the last two decades, problems with treatment of newly emerged, reemerged, or persistent infectious diseases necessitated researchers to develop new and/or improved antibody-based therapeutic approaches. This article reviews some information on the use of antibodies for the treatment of infectious diseases, with special reference to the most seminal discoveries and current advances as well as available treatment approaches in this field.

Keywords: Antibody therapy; infectious diseases; immunoglobulin

Language: English

Document Type: Review article

Publication date: 2002-07-01