Use of Radiation Hybrid panels to map genetic loci

Authors: Friedman, James; Walter, Michael

Source: Molecular Biotechnology, Volume 19, Number 2, October 2001 , pp. 205-210(6)

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Abstract:

The mapping of genetic loci within organisms has been accelerated by the advent of Radiation Hybrid (RH) panels. These panels are available for humans and non-humans including mice, baboon, rat, and canine. This article contains a general protocol for the use of the Genebridge 4 whole genome RH panel to map a human locus. This protocol may also be adjusted to suit the other RH panels currently available.

Keywords: Mapping; radiation hybrid panels

Document Type: Research article

DOI: http://dx.doi.org/10.1385/MB:19:2:205

Affiliations: 1: Department of Ophthalmology, University of Alberta, Rm. 832 Medical Sciences Building, T6G-2H7, Edmonton, Alberta, Canada, Email: jafriedm@ualberta.ca

Publication date: 2001-10-01