Cystic medullary thyroid carcinoma: Report of a case with morphological and clinical correlations

Authors: Fadda, Guido¹; Mulè, Antonino; Rufini, Vittoria¹; Ardito, Guglielmo²; Revelli, Luca; Fiorino, Marilena; Capelli, Arnaldo

Source: Endocrine Pathology, Volume 11, Number 4, December 2000 , pp. 373-377(5)

Publisher: Humana Press

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Abstract:

Cystic lesions of the thyroid are common findings. Although many thyroid cysts are of benign, some cases of hemorrhagic degenerative changes occur in neoplastic nodules, mostly follicular neoplasms and papillary carcinomas. The occurrence of hemorrhagic changes in medullary carcinomas has never been documented with aspirative cytological and histological pictures to the best of our knowledge. A case of medullary thyroid carcinoma with a large central hemorrhagic cyst is described, and the literature regarding the pathogenesis of this regression and the occurrence of cystic neoplasms in the thyroid is reviewed.

Keywords: Medullary thyroid carcinoma; thyroid pathology; fine-needle aspiration biopsy

Document Type: Research article

DOI: http://dx.doi.org/10.1385/EP:11:4:373

Affiliations: 1: Division of Anatomic Pathology and Histology, Division of Nuclear Medicine, Catholic University of Sacred Heart, Rome, Italy, 2: Division of Surgery, Catholic University of Sacred Heart, Rome, Italy,

Publication date: 2000-12-01