A new flavanone, reflexin, from Cuscuta reflexa and its selective sensing of nitric oxide

Authors: Tripathi, V.¹; Yadav, S.²; Upadhyay, A.²

Source: Applied Biochemistry and Biotechnology, Volume 127, Number 1, October 2005 , pp. 63-67(5)

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Abstract:

A new compound, reflexin, 5-hydroxy-7-methoxy-6-(2,3-epoxy-3-methylbutyl)-flavanone, is isolated from the stems of Cuscuta reflexa along with three other known compounds. This new compound has good potential for application especially in the photoactivity of reflexin. It was found to be sensitive to glutathione, forming a fluorescent product that is utilized for sensing nitric oxide (NO). The lowest detection limit of NO analysis was found to be 0.05 μM.

Keywords: Reflexin; Nitric oxide; Cuscuta reflexa; glutathione; nitrosothiol

Document Type: Research article

DOI: http://dx.doi.org/10.1385/ABAB:127:1:063

Affiliations: 1: Department of Chemistry, Banaras Hindu University, 221 005, Varanasi, India, Email: sbyadavbhu@rediffmail.com 2: Department of Chemistry, Banaras Hindu University, 221 005, Varanasi, India,

Publication date: 2005-10-01