Determination of triclosan in antiperspirant gels by first-order derivative spectrophotometry
Abstract:A first-order derivative UV spectrophotometric method was developed to determine triclosan, a broad-spectrum antimicrobial agent, in health care products containing fragrances which could interfere the determination as impurities. Different extraction methods were compared. Triclosan was extracted with chloroform and diluted with ethanol followed by the derivative spectrophotometric measurement. The interference of fragrances was completely eliminated. The calibration graph was found to be linear in the range of 7.5–45 μg·mL–1. The method is simple, rapid, sensitive and proper to determine triclosan in fragrance-containing health care products.
Document Type: Research Article
Publication date: October 1, 2011
More about this publication?
- Pharmazie is one of the world's leading pharmaceutical journals. As a peer-reviewed scientific journal, DiePharmazie is regularly indexed in Current Contents/Life Sciences, Excerpta Medica, Analytical Abstracts, International Pharmaceutical Abstracts, Beilstein Current Facts in Chemistry, Chemical Engineering and Biotechnology Abstracts (CEABA) and Science Citation Index.
- Information for Authors
- Submit a Paper
- Subscribe to this Title
- Terms & Conditions
- ingentaconnect is not responsible for the content or availability of external websites