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Open Access Degradation kinetics of butylmethoxydibenzoylmethane (avobenzone) in aqueous solution

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Abstract:

The degradation kinetics of avobenzone in aqueous solution was studied at 60 ± 0.2 °C over a pH range of 2.0–10.0. The degradation rates were determined by high performance liquid chromatography. The reaction is found to follow first-order kinetics and the rate constant for the decomposition at 25 °C is estimated by extrapolation. The breakdown of avobenzone is shown to be hydroxide ion catalyzed and the Arrhenius plots showed the temperature dependence of avobenzone degradation.

Document Type: Research Article

DOI: http://dx.doi.org/10.1691/ph.2007.10.6299

Affiliations: 1: DMI Inc., Wharton, NJ, USA 2: Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria, West Africa

Publication date: October 1, 2007

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  • Pharmazie is one of the world's leading pharmaceutical journals. As a peer-reviewed scientific journal, DiePharmazie is regularly indexed in Current Contents/Life Sciences, Excerpta Medica, Analytical Abstracts, International Pharmaceutical Abstracts, Beilstein Current Facts in Chemistry, Chemical Engineering and Biotechnology Abstracts (CEABA) and Science Citation Index.
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