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Open Access Degradation kinetics of butylmethoxydibenzoylmethane (avobenzone) in aqueous solution

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The degradation kinetics of avobenzone in aqueous solution was studied at 60 ± 0.2 °C over a pH range of 2.0–10.0. The degradation rates were determined by high performance liquid chromatography. The reaction is found to follow first-order kinetics and the rate constant for the decomposition at 25 °C is estimated by extrapolation. The breakdown of avobenzone is shown to be hydroxide ion catalyzed and the Arrhenius plots showed the temperature dependence of avobenzone degradation.

Document Type: Research Article


Affiliations: 1: DMI Inc., Wharton, NJ, USA 2: Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria, West Africa

Publication date: October 1, 2007

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  • Pharmazie is a leading journal in the field of pharmaceutical sciences. As a peer-reviewed scientific journal, Pharmazie is regularly indexed in the relevant databases like Web of science, Journal Citation Reports and many others. The journal is open for submissions from the whole spectrum of pharnaceutical sciences including Pharmaceutical Chemistry, Experimental and Clinical Pharmacology, Drug Analysis, Pharmaceutics, Pharmaceutical Biology, Clinical Pharmacy etc.
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