A validated UV spectrophotometric method for estimation of nebivolol hydrochloride in bulk and pharmaceutical formulation
A simple, sensitive and accurate UV spectrophotometric method was developed for the assay of nebivolol hydrochloride in raw material and tablets. Validation of the method yielded good results concerning range, linearity, precision and accuracy. The absorbance was measured at 282 nm
for nebivolol hydrochloride tablet solution. The linearity range was found to be 5–50 μg/mL for the drug. It was found that the excipients present in the commercial formulation did not interfere with the method.
Document Type: Research Article
Affiliations: 1: Pharmaceutics Research Laboratory-II, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India 2: Pharmaceutics Research Laboratory-II, Department of Pharmaceutical Technology, Jadavpur University, Strasse, Kolkata, 700 032, India, Email: [email protected]
Publication date: 01 July 2007
- Pharmazie is a leading journal in the field of pharmaceutical sciences. As a peer-reviewed scientific journal, Pharmazie is regularly indexed in the relevant databases like Web of science, Journal Citation Reports and many others. The journal is open for submissions from the whole spectrum of pharnaceutical sciences including Pharmaceutical Chemistry, Experimental and Clinical Pharmacology, Drug Analysis, Pharmaceutics, Pharmaceutical Biology, Clinical Pharmacy etc.
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