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Open Access Metabolism of parthenin by Beauveria bassiana ATCC 7159

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Two new metabolites were isolated from the biotransformation reaction of parthenin by Beauveria bassiana ATCC 7159 along with the known naturally occurring sesquiterpene lactones hymenolin and dihydrocoronopilin. The new metabolites: are 3β,4β,6β-trihydroxy-10αH,11α-methyl-ambrosa-1-en-12-oic acid-γ-lactone and 3α,6β-dihydroxy-4β-hydroperoxy-10αH, 11α-methyl-ambrosa-1-en-12-oic acid-γ-lactone. The structure elucidation of these compounds was achieved by different spectroscopic methods.

Document Type: Research Article

DOI: http://dx.doi.org/10.1691/ph.2007.3.6628

Affiliations: 1: Department of Pharmacognosy, Faculty of Pharmacy, University of Mansoura, Mansoura, Egypt 2: Department of Pharmacognosy, Faculty of Pharmacy, University of Mansoura, Mansoura, 35516, Egypt, Email: amarzouk2003@yahoo.co.uk

Publication date: March 1, 2007

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  • Pharmazie is one of the world's leading pharmaceutical journals. As a peer-reviewed scientific journal, DiePharmazie is regularly indexed in Current Contents/Life Sciences, Excerpta Medica, Analytical Abstracts, International Pharmaceutical Abstracts, Beilstein Current Facts in Chemistry, Chemical Engineering and Biotechnology Abstracts (CEABA) and Science Citation Index.
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