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Open Access Metabolism of parthenin by Beauveria bassiana ATCC 7159

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Abstract:

Two new metabolites were isolated from the biotransformation reaction of parthenin by Beauveria bassiana ATCC 7159 along with the known naturally occurring sesquiterpene lactones hymenolin and dihydrocoronopilin. The new metabolites: are 3β,4β,6β-trihydroxy-10αH,11α-methyl-ambrosa-1-en-12-oic acid-γ-lactone and 3α,6β-dihydroxy-4β-hydroperoxy-10αH, 11α-methyl-ambrosa-1-en-12-oic acid-γ-lactone. The structure elucidation of these compounds was achieved by different spectroscopic methods.

Document Type: Research Article

DOI: https://doi.org/10.1691/ph.2007.3.6628

Affiliations: 1: Department of Pharmacognosy, Faculty of Pharmacy, University of Mansoura, Mansoura, Egypt 2: Department of Pharmacognosy, Faculty of Pharmacy, University of Mansoura, Mansoura, 35516, Egypt, Email: amarzouk2003@yahoo.co.uk

Publication date: 2007-03-01

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  • Pharmazie is a leading journal in the field of pharmaceutical sciences. As a peer-reviewed scientific journal, Pharmazie is regularly indexed in the relevant databases like Web of science, Journal Citation Reports and many others. The journal is open for submissions from the whole spectrum of pharnaceutical sciences including Pharmaceutical Chemistry, Experimental and Clinical Pharmacology, Drug Analysis, Pharmaceutics, Pharmaceutical Biology, Clinical Pharmacy etc.
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