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Open Access Three new pimaren diterpenoids from marine mangrove plant, Bruguiera gymnorrhiza

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Three new pimaren diterpenoids, ent-8(14)-pimarene-15R,16-diol (1), ent-8(14)-pimarene-1α,15R,16-triol (2), and (5R, 9S, 10R, 13S, 15S)-ent-8(14)-pimarene-1-oxo-15R,16-diol (3), along with three known diterpenoids (4–6) have been isolated from the stem of mangrove plant Bruguiera gymnorrhiza. The structures of compounds 1–3 were determined by extensive spectroscopic (2D NMR, MS, IR, and CD) analysis, and 3 and 5 showed moderate cytotoxic activities against L-929 and K562, respectively.

Document Type: Research Article

Affiliations: 1: State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, P.R. China 2: State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, 100083, P.R. China, Email:

Publication date: 2005-09-01

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