Three new pimaren diterpenoids from marine mangrove plant, Bruguiera gymnorrhiza
Source: Die Pharmazie - An International Journal of Pharmaceutical Sciences, Volume 60, Number 9, 1 September 2005 , pp. 705-707(3)
Abstract:Three new pimaren diterpenoids, ent-8(14)-pimarene-15R,16-diol (1), ent-8(14)-pimarene-1α,15R,16-triol (2), and (5R, 9S, 10R, 13S, 15S)-ent-8(14)-pimarene-1-oxo-15R,16-diol (3), along with three known diterpenoids (4–6) have been isolated from the stem of mangrove plant Bruguiera gymnorrhiza. The structures of compounds 1–3 were determined by extensive spectroscopic (2D NMR, MS, IR, and CD) analysis, and 3 and 5 showed moderate cytotoxic activities against L-929 and K562, respectively.
Document Type: Research Article
Affiliations: 1: State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, P.R. China 2: State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, 100083, P.R. China, Email: email@example.com
Publication date: September 1, 2005
- Pharmazie is one of the world's leading pharmaceutical journals. As a peer-reviewed scientific journal, DiePharmazie is regularly indexed in Current Contents/Life Sciences, Excerpta Medica, Analytical Abstracts, International Pharmaceutical Abstracts, Beilstein Current Facts in Chemistry, Chemical Engineering and Biotechnology Abstracts (CEABA) and Science Citation Index.
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