Authors: Petrillo, Jennifer; Cairns, John

Source: Expert Review of Pharmacoeconomics and Outcomes Research, Volume 8, Number 5, October 2008 , pp. 453-461(9)

Publisher: Expert Reviews

Abstract:

Quality-adjusted life-years (QALYs) play an important role in reimbursement decisions when one of the criteria is the cost-effectiveness of the health technology. While for many generic QALYs (e.g., based on the EQ-5D) are viewed as the gold standard, there has been a considerable increase in interest in using condition-specific data to generate QALYs. There are two main methods: mapping from the condition-specific data to a generic health-related quality of life measure; and direct valuation of condition-specific health states. Whether one believes condition-specific data are useful even if generic QALY data are available, or simply that condition-specific data are helpful in the absence of generic measures of health-related quality of life, it is timely to review recent research activity directed at making greater use of condition-specific data to inform assessments of cost-effectiveness.

Keywords: condition-specific measure; economic evaluation; EQ-5D; mapping

Document Type: Research article

DOI: http://dx.doi.org/10.1586/14737167.8.5.453

Affiliations: 1: London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK; United BioSource Corporation, 20 Bloomsbury Square, London WC1A 2NS, UK., Email: jennifer.petrillo@lshtm.ac.uk

Publication date: 2008-10-01

More about this publication?

• Expert Review of Pharmacoeconomics & Outcomes Research provides expert commentary on cost-benefit and pharmacoeconomic issues relating to the clinical use of drugs and therapeutic approaches. Coverage includes pharmacoeconomics and quality-of-life research, therapeutic outcomes, evidence-based medicine and cost-benefit research.
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