Economic impact of poor compliance with pharmaceuticals

Author: Hughes, Dyfrig A

Source: Expert Review of Pharmacoeconomics and Outcomes Research, Volume 2, Number 4, August 2002 , pp. 327-335(9)

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Abstract:

Poor compliance with prescribed drug regimens is a widespread phenomenon which results in decreased efficacy and is often associated with increased medical expenditures due to treatment failure and/or adverse events. This review examines the issues relating to the measurement of compliance and the clinical and economic consequences of noncompliant drug taking behavior. The results of a literature review, identifying pharmacoeconomic evaluations which measured compliance, are presented. It concludes by highlighting the importance of accounting for poor compliance in pharmacoeconomic evaluations and suggests ways in which compliance may be incorporated in economic models.

Keywords: adherence; compliance; cost-effectiveness analysis; pharmacoeconomics

Document Type: Research article

DOI: http://dx.doi.org/10.1586/14737167.2.4.327

Publication date: 2002-08-01

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Expert Review of Pharmacoeconomics & Outcomes Research provides expert commentary on cost-benefit and pharmacoeconomic issues relating to the clinical use of drugs and therapeutic approaches. Coverage includes pharmacoeconomics and quality-of-life research, therapeutic outcomes, evidence-based medicine and cost-benefit research.
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