Authors: Lysaker, Paul H; Outcalt, Samantha D; Ringer, Jamie M

Source: Expert Review of Neurotherapeutics, Volume 10, Number 7, July 2010 , pp. 1143-1151(9)

Publisher: Expert Reviews

Abstract:

Interest has arisen in the role stressors play in the development and outcome of schizophrenia. This article examines one such stressor - trauma experienced prior to the onset of illness. We discuss research on the incidence, types and correlates of trauma in schizophrenia, and review work suggesting trauma may increase risk for schizophrenia. Studies are further detailed that have examined links between trauma and heightened levels of positive symptoms and anxiety, and poorer social, vocational and treatment outcomes. Here, literature on approaches to addressing trauma among persons with schizophrenia is presented, along with a commentary that points to the need for research on how trauma might increase the risk for the development of schizophrenia and worsen the symptoms and treatment outcome of individuals in recovery from this illness.

Keywords: anxiety; positive symptoms; psychosocial function; psychotherapy; recovery; schizophrenia; trauma

Document Type: Research article

DOI: http://dx.doi.org/10.1586/ern.10.36

Affiliations: 1: 1Roudebush VA Medical Center, Indianapolis, IN, USA; Roudebush VA Medical Center, Day Hospital 116H, 1481 West 10th Street, Indianapolis, IN 46202, USA

Publication date: 2010-07-01

More about this publication?

• Expert Review of Neurotherapeutics provides expert commentary on the use of drugs and medicines in clinical neurology and neuropsychiatry. Coverage includes disease management, new medicines and drugs in neurology, therapeutic indications, diagnostics, medical treatment guidelines and neurological diseases such as stroke, epilepsy, Alzheimer's and Parkinson's.
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