Treatment of status epilepticus

Authors: Miller, Laura C; Drislane, Frank W

Source: Expert Review of Neurotherapeutics, Volume 8, Number 12, December 2008 , pp. 1817-1827(11)

Buy & download fulltext article:

Price: $73.00 plus tax (Refund Policy)

Abstract:

Generalized convulsive status epilepticus is a neurologic and medical emergency, with significant morbidity and mortality. First-line treatment includes administration of intravenous benzodiazepines. Second-line agents include intravenous phenytoin, phenobarbital, valproate and levetiracetam. Refractory status epilepticus necessitates the use of anesthetic agents such as pentobarbital, midazolam or propofol, with monitoring of treatment effect by continuous EEG. Nonconvulsive status epilepticus should be treated expeditiously but is not as threatening to health as convulsive status epilepticus.

Keywords: antiepileptic drug; convulsive status epilepticus; EEG; electroencephalogram; nonconvulsive status epilepticus; status epilepticus; treatment

Document Type: Research article

DOI: http://dx.doi.org/10.1586/14737175.8.12.1817

Affiliations: 1: Comprehensive Epilepsy Center, Beth Israel Deaconess Medical Center, Department of Neurology, Harvard Medical School, Boston, MA 02215, USA

Publication date: 2008-12-01

More about this publication?

Expert Review of Neurotherapeutics provides expert commentary on the use of drugs and medicines in clinical neurology and neuropsychiatry. Coverage includes disease management, new medicines and drugs in neurology, therapeutic indications, diagnostics, medical treatment guidelines and neurological diseases such as stroke, epilepsy, Alzheimer's and Parkinson's.
Editorial Board
Information for Authors
Submit a Paper
Subscribe to this Title
Information for Advertisers
Terms & Conditions
Information for Librarians
Free Trials
ingentaconnect is not responsible for the content or availability of external websites