Prevention and treatment of congenital toxoplasmosis

Author: Petersen, Eskild

Source: Expert Review of Anti-Infective Therapy, Volume 5, Number 2, April 2007 , pp. 285-293(9)

Buy & download fulltext article:

Price: $73.00 plus tax (Refund Policy)

Abstract:

Infection with Toxoplasma gondii is transmitted to man by infected meat or meat products and by contact with soil or surface water. In theory, prevention by hygienic measures is possible, but this has never been proved to work in practice. Therefore, pre- and postnatal screening has been implemented in several countries aiming at early diagnosis. However, data on the effect of treatment are limited and no randomized, controlled trials have been performed. The risk of T. gondii infection in Europe is declining and studies using historical controls from earlier decades cannot be used for decision making. The screening of pregnant women or neonates makes the assumption that any children diagnosed can be offered an effective treatment. There is an urgent need to test new drugs and demonstrate, using randomized, controlled trials, that the currently used drugs are effective.

Keywords: disease burden; control; prevention; Toxoplasma gondii; treatment

Document Type: Research article

DOI: http://dx.doi.org/10.1586/14787210.5.2.285

Publication date: 2007-04-01

More about this publication?

Expert Review of Anti-infective Therapy provides expert reviews on therapeutics and diagnostics in the treatment of infectious disease. Coverage includes antibiotics, drug resistance, drug therapy, infectious disease medicine, antibacterial, antimicrobial, antifungal and antiviral approaches, and diagnostic tests.
Editorial Board
Information for Authors
Submit a Paper
Subscribe to this Title
Information for Advertisers
Terms & Conditions
Information for Librarians
Free Trials
ingentaconnect is not responsible for the content or availability of external websites