Treatment of childhood Plasmodium falciparum malaria: current challenges

Authors: Bell, David J; Molyneux, Malcolm E

Source: Expert Review of Anti-Infective Therapy, Volume 5, Number 1, February 2007 , pp. 141-152(12)

Buy & download fulltext article:

Price: $73.00 plus tax (Refund Policy)

Abstract:

Malaria continues to be a major cause of mortality and morbidity in tropical countries. Infection with Plasmodium falciparum may be asymptomatic, cause an uncomplicated febrile illness or give rise to severe disease complicated by coma, acidosis or severe anemia. Treatment of the febrile illness with two drugs - preferably in the form of an artemisinin-containing combination therapy - is now widely recommended, both for greater efficacy and in order to delay the evolution of drug resistance. The clinical picture of severe malaria differs according to the age and immune status of the individual; treatment requires a range of supportive measures, as well as an efficacious antimalarial drug. Insecticide-treated bednets and presumptive treatment programs are increasingly deployed in malaria control programs, while vaccines are showing promise.

Keywords: complications; diagnosis; IPT; malaria; Plasmodium falciparum; rapid diagnostic tests; treatment

Document Type: Research article

DOI: http://dx.doi.org/10.1586/14787210.5.1.141

Publication date: 2007-02-01

More about this publication?

Expert Review of Anti-infective Therapy provides expert reviews on therapeutics and diagnostics in the treatment of infectious disease. Coverage includes antibiotics, drug resistance, drug therapy, infectious disease medicine, antibacterial, antimicrobial, antifungal and antiviral approaches, and diagnostic tests.
Editorial Board
Information for Authors
Submit a Paper
Subscribe to this Title
Information for Advertisers
Terms & Conditions
Information for Librarians
Free Trials
ingentaconnect is not responsible for the content or availability of external websites