Hospital-based strategies to reduce antibiotic resistance: are they valid in the community setting?

Authors: Tillotson, Glenn S; Blondeau, Joseph M; Carroll, Joy

Source: Expert Review of Anti-Infective Therapy, Volume 5, Number 1, February 2007 , pp. 53-59(7)

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Abstract:

Antimicrobial resistance is an increasing problem worldwide in both the hospital and community settings. Various approaches have been proposed and tested mainly in the hospital environment to reduce this problem; however, few of these have been examined from the perspective of applicability to reversing community-based resistance. It is clear that, in addition to specific antibiotic usage campaigns, a major educational initiative for both prescribers and patients alike is required for the full societal impact of growing antibiotic resistance to be appreciated. This inexorable increase is occurring in the face of a dearth of new antibiotics for community use and even fewer for treating resistant nosocomial Gram-negative species. The possible strategies and consequences are discussed.

Keywords: antibiotic resistance; community infections; nosocomial pathogens

Document Type: Research article

DOI: http://dx.doi.org/10.1586/14787210.5.1.53

Publication date: 2007-02-01

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Expert Review of Anti-infective Therapy provides expert reviews on therapeutics and diagnostics in the treatment of infectious disease. Coverage includes antibiotics, drug resistance, drug therapy, infectious disease medicine, antibacterial, antimicrobial, antifungal and antiviral approaches, and diagnostic tests.
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