Premature cardiovascular disease in young women with heterozygous familial hypercholesterolemia

Authors: van der Graaf, Anouk; Hutten, Barbara A; Kastelein, John JP; Vissers, Maud N

Source: Expert Review of Cardiovascular Therapy, Volume 4, Number 3, May 2006 , pp. 345-351(7)

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Abstract:

Heterozygous familial hypercholesterolemia is associated with elevated low-density lipoprotein cholesterol levels and the development of premature cardiovascular disease. Despite this general statement, data regarding the incidence of cardiovascular disease in young women with familial hypercholesterolemia are lacking. In this review, information of age-specific incidence, risk factors and therapeutic avenues in women with heterozygous familial hypercholesterolemia are discussed.

Keywords: cardiovascular disease; familial hypercholesterolemia; low-density lipoprotein; statins; women

Document Type: Research article

DOI: http://dx.doi.org/10.1586/14779072.4.3.345

Publication date: 2006-05-01

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Expert Review of Cardiovascular Therapy provides expert commentary on the clinical applications of the new medicines, therapeutic agents and diagnostics in cardiovascular disease. Coverage inculdes drug therapy, heart disease, vascular disorders, hypertension, cholesterol in cardiovascular disease, heart disease, stroke, heart failure and cardiovascular surgery.
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