Photodynamic therapy for superficial bladder cancer

Authors: Shackley, David C; Briggs, Catherine; Whitehurst, Colin; Betts, Christopher D; O'Flynn, Kieran J; Clarke, Noel W; Moore, James V

Source: Expert Review of Anticancer Therapy, Volume 1, Number 4, December 2001 , pp. 523-530(8)

Publisher: Expert Reviews

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Abstract:

In photodynamic therapy, a photosensitizing drug is activated by visible light and in the presence of oxygen, results in local cell death. This evolving modality is now being used to treat and palliate a very wide variety of human solid tumors and carcinoma-in-situ lesions. With regard to bladder cancer, advances in drug development and modern light delivery techniques mean that photodynamic therapy shows promise in the treatment of superficial bladder cancer resistant to conventional treatments.

Keywords: 5-aminolaevulinic acid; bladder cancer; dihematoporphyrin-ether; photodynamic therapy; transitional cell carcinoma

Document Type: Research article

DOI: http://dx.doi.org/10.1586/14737140.1.4.523

Publication date: 2001-12-01

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Expert Review of Anticancer Therapy provides expert appraisal and commentary on the major trends in cancer care and highlights the performance of new therapeutic and diagnostic approaches.
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