Oxidative stress response: a proteomic view

Authors: Rabilloud, Thierry; Chevallet, Mireille; Luche, Sylvie; Leize-Wagner, Emmanuelle

Source: Expert Review of Proteomics, Volume 2, Number 6, December 2005 , pp. 949-956(8)

Buy & download fulltext article:

Price: $73.00 plus tax (Refund Policy)

Abstract:

The oxidative stress response is characterized by various effects on a range of biologic molecules. When examined at the protein level, both expression levels and protein modifications are altered by oxidative stress. While these effects have been studied in the past by classic biochemical methods, the recent onset of proteomics methods has allowed the oxidative stress response to be studied on a much wider scale. The input of proteomics in the study of oxidative stress response and in the evidence of an oxidative stress component in biologic phenomena is reviewed in this paper.

Keywords: 2D electrophoresis; mass spectrometry; oxidative stress; peroxiredoxin; protein carbonyls; protein expression; protein nitration; proteomics; superoxide dismutase

Document Type: Research article

DOI: http://dx.doi.org/10.1586/14789450.2.6.949

Publication date: 2005-12-01

More about this publication?

Expert Review of Proteomics explores technologies, methods and discoveries from the field of proteomics to advance scientific understanding of the many varied roles protein expression plays in human health and disease.
Editorial Board
Information for Authors
Submit a Paper
Subscribe to this Title
Information for Advertisers
Terms & Conditions
Information for Librarians
Free Trials
ingentaconnect is not responsible for the content or availability of external websites