Verteporfin photodynamic therapy in the age of antiangiogenic therapy

Authors: Barbazetto, Irene A; Takahashi, Beatriz S

Source: Expert Review of Ophthalmology, Volume 3, Number 4, August 2008 , pp. 365-383(19)

Publisher: Expert Reviews

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Abstract:

Photodynamic therapy with verteporfin was the first approved pharmacological treatment for choroidal neovascularization in patients with age-related macular degeneration, pathologic myopia and ocular histoplasmosis syndrome. With the introduction of anti-VEGF therapy, verteporfin photodynamic therapy is no longer the first line of treatment for neovascular age-related macular degeneration. Ongoing clinical trials will determine the future role of PDT alone or as part of a more individualized combination therapy.

Keywords: choroidal neovascularization; combination therapy; intraocular anti-VEGF therapy; macular degeneration; photodynamic therapy; verteporfin

Document Type: Research article

DOI: http://dx.doi.org/10.1586/17469899.3.4.365

Affiliations: 1: VRM Consultants of New York, 460 Park Avenue, 5th Floor, New York, NY 10022, USA., Email: ib206@columbia.edu

Publication date: 2008-08-01

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