Sutureless amniotic membrane transplantation

Authors: Kheirkhah, Ahmad; Li, Wei; Casas, Victoria; Tseng, Scheffer CG

Source: Expert Review of Ophthalmology, Volume 1, Number 1, October 2006 , pp. 49-62(14)

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Abstract:

Transplantation of cryopreserved amniotic membrane (AM) is a widely accepted surgical procedure to promote epithelial healing and to reduce inflammation, scarring and emerging neovascularization on the ocular surface. Clinical uses of AM for ocular surface reconstruction can be categorized either as a permanent graft or as a biological bandage. Permanent graft of AM has been used to replace the deficient or destroyed ocular surface tissue (cornea and/or conjunctiva) caused by disease or surgery and to promote regeneration, rather than repair, of the ocular surface. The main indication for using AM as a biological bandage is to suppress inflammation on the ocular surface caused by various diseases and insults, so as to promote epithelial healing with minimal or no scarring. Sutureless AM transplantation with fibrin glue or ProKera™ is a safe and easy method that avoids complications related to sutures and shortens the time of surgery.

Keywords: amniotic membrane; band keratopathy; bullous keratopathy; chemical burn; cicatricial ocular disease; conjunctivochalasis; corneal ulcer; limbal stem-cell deficiency; pterygium

Document Type: Research article

DOI: http://dx.doi.org/10.1586/17469899.1.1.49

Publication date: 2006-10-01

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Expert Review of Ophthalmology provides an important platform for commentary and debate on current and emerging approaches in ocular medicine.
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