Endocrinopathy of HFE-related hemochromatosis

Authors: O'Sullivan, Eoin P; Walsh, C Howel

Source: Expert Review of Endocrinology and Metabolism, Volume 2, Number 2, March 2007 , pp. 277-286(10)

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Abstract:

Hereditary hemochromatosis is a condition affecting many organs, as reflected by the fact that it is managed variably by hematologists, gastroenterologists, rheumatologists and endocrinologists, depending on local preferences. A potential pitfall of this approach is that certain aspects of diagnosis and management may be overlooked, particularly if they fall beyond the normal scope of practice of the specialist physician concerned. The purpose of this article is to review the nature of the endocrine complications of hereditary hemochromatosis, which have changed dramatically since the condition was first described over 100 years ago.

Keywords: adrenal; diabetes; endocrinopathy; hemochromatosis; hereditary hypogonadism; iron; pituitary thyroid

Document Type: Research article

DOI: http://dx.doi.org/10.1586/17446651.2.2.277

Publication date: 2007-03-01

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Expert Review of Endocrinology & Metabolism provides extensive coverage of state-of-the-art research and clinical advancements in the field of endocrine control and metabolism, with a focus on screening, prevention, diagnostics, existing and novel therapeutics, as well as related molecular genetics, pathophysiology and epidemiology
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