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Pharmacogenomics provides the community with an essential resource for keeping abreast of the latest developments in new pharmacogenomic initiatives, emerging technologies for accessing genomic information and the development of novel diagnostic products and strategies.

Publisher: Future Medicine

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Volume 10, Number 1, January 2009

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Editorial

Setting future standards for KRAS testing in colorectal cancer
pp. 1-3(3)
Authors: van Krieken, Han; Tol, Jolien

News & Views

Interview
pp. 9-12(4)
Author: Klein, Roger D

Research Highlights
pp. 13-16(4)
Authors: Veraitch, Ophelia; Stebbing, Justin

Pharmacogenetics of debrisoquine and its use as a marker for CYP2D6 hydroxylation capacity
pp. 17-28(12)
Authors: LLerena, Adriáán; Dorado, Pedro; Peññas-Lledóó, Eva M

Research Article

Glutathione S-transferase T1- and M1-null genotypes and coronary artery disease risk in patients with Type 2 diabetes mellitus Cardiovasc
pp. 29-34(6)
Authors: Manfredi, Samantha; Calvi, Debora; del Fiandra, Martina; Botto, Nicoletta; Biagini, Andrea; Andreassi, Maria Grazia

Need for reassessment of reported CYP2C19 allele frequencies in various populations in view of CYP2C19*17 discovery: the case of Greece
pp. 43-49(7)
Authors: Ragia, Georgia; Arvanitidis, Kostas I; Tavridou, Anna; Manolopoulos, Vangelis G

Measurements of EGFR expression on circulating tumor cells are reproducible over time in metastatic breast cancer patients
pp. 51-57(7)
Authors: Payne, Rachel E; Yagüüe, Ernesto; Slade, Martin J; Apostolopoulos, Christos; Jiao, Long R; Ward, Becky; Coombes, R Charles; Stebbing, Justin

Review

EGFR-targeted therapies in lung cancer: predictors of response and toxicity
pp. 59-68(10)
Authors: Heist, Rebecca Suk; Christiani, David

Pharmacogenomics of gemcitabine in non-small-cell lung cancer and other solid tumors
pp. 69-80(12)
Authors: Danesi, Romano; Altavilla, Giuseppe; Giovannetti, Elisa; Rosell, Raffael

Predictive role of C677T MTHFR polymorphism in variable efficacy of photodynamic therapy for neovascular age-related macular degeneration
pp. 81-95(15)
Authors: Parmeggiani, Francesco; Gemmati, Donato; Costagliola, Ciro; Sebastiani, Adolfo; Incorvaia, Carlo

Pharmacogenomics of IFN-ββ in multiple sclerosis: towards a personalized medicine approach
pp. 97-108(12)
Authors: Vosslamber, Saskia; van Baarsen, Lisa GM; Verweij, Cornelis L

Special Report

4th US FDA--Drug Information Association pharmacogenomics workshop, held 10--12 December, 2007
pp. 111-115(5)
Authors: Frueh, Felix W; Salerno, Ronald A; Lesko, Lawrence J; Hockett, Richard D

Developing the evidence base for applying pharmacogenomics: proceeds from DIA Workshop IV -- Breakout Session 1
pp. 117-125(9)
Authors: Armstrong, Martin; Bromley, Christina; Cohen, Nadine; Hunt, Christine M; O''Neill, Robert; Power, Aidan

Drug--diagnostic codevelopment strategies: FDA and industry dialog at the 4th FDA/DIA/PhRMA/PWG/BIO Pharmacogenomics Workshop
pp. 127-136(10)
Authors: Hinman, Lois; Spear, Brian; Tsuchihashi, Zenta; Kelly, James; Bross, Peter; Goodsaid, Federico; Kalush, Francis

Fit-for-purpose pharmacogenomic biomarkers in drug development: a project team case study with ``what-ifs''
pp. 137-147(11)
Authors: Surh, Linda C; Lesko, Lawrence J; Hobbs, Stuart; Gutman, Steve; Minasian, Lori M; Pasqua, Oscar E Della; Austin, MJ Finley; Lu, Kan

Payer perspectives on pharmacogenomics testing and drug development
pp. 149-151(3)
Authors: Epstein, Robert S; Frueh, Felix W; Geren, Dawn; Hummer, Doris; McKibbin, Scott; O''Connor, Susan; Randhawa, Gurvaneet; Zelman, Benjamin

Acknowledgements

Acknowledgements
pp. 155-155(1)

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