Classification and categorization of psoriatic arthritis

Author: Helliwell, Philip S

Source: Future Rheumatology, Volume 1, Number 4, August 2006 , pp. 501-509(9)

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Abstract:

For over 30 years, investigators have used the simple but nonvalidated classification criteria suggested by Moll and Wright. Several authors have suggested modifications to these, but most remain invalid or require human leukocyte antigen analysis. Now, a worldwide initiative has developed new criteria which include both clinical and radiological features. These will require further study before they are fully adopted for future studies, although improved performance should result in less variation between study cohorts. The recurring question of disease heterogeneity continues to occupy researchers in this field. Despite recent pleas to abandon the original five subgroups, a case can be made for retaining at least the two subgroups of peripheral and axial disease and, possibly, splitting the peripheral disease into oligo- and polyarthritis.

Keywords: classification criteria; clinical features; diagnosis; psoriatic arthritis; spondyloarthropathy

Document Type: Research article

DOI: http://dx.doi.org/10.2217/17460816.1.4.501

Affiliations: 1: University of Leeds, Academic Unit of Musculoskeletal & Rehabilitation Medicine, 36, Clarendon Road, Leeds, LS2 9NZ, UK., Email: p.helliwell@leeds.ac.uk

Publication date: 2006-08-01

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Future Rheumatology provides analysis and commentary on our understanding of disease mechanisms, emerging therapeutic strategies and new diagnostic approaches. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this expanding area of specialization.
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