Paget's disease of the hip: surgical management

Authors: Parvizi, Javad; Restrepo, Camilo; Sim, Franklin H

Source: Future Rheumatology, Volume 1, Number 3, June 2006 , pp. 373-377(5)

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Abstract:

Paget's bone disease is a rare pathology in which nonorganized resorption and deposition of new bone takes place, leading to structural changes that, in conjunction with increased local vascularity, become symptomatic.The disease affects mostly the pelvic area, including the proximal femur, but the flat bones and skull are also frequently involved. Treatment includes pain management, bisphosphonates and surgery for the correction of deformities. When the hip is compromised these changes eventually develop into arthrosis and total hip arthroplasty becomes an alternative therapy, shown to be successful in restoring patients' function.

Keywords: bisphosphonates; bone deposit; heterotopic; ossification; osteosarcoma; Paget's disease; resorption; total hip arthroplasty

Document Type: Research article

DOI: http://dx.doi.org/10.2217/17460816.1.3.373

Affiliations: 1: Jefferson Hospital, Rothman Institute of Orthopedics, PA, USA

Publication date: 2006-06-01

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Future Rheumatology provides analysis and commentary on our understanding of disease mechanisms, emerging therapeutic strategies and new diagnostic approaches. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this expanding area of specialization.
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