Future directions for recanalization therapy in acute ischemic stroke

Authors: Willey, Joshua; Schumacher, H Christian; Meyers, Philip M

Source: Future Neurology, Volume 1, Number 1, January 2006 , pp. 107-116(10)

Buy & download fulltext article:

Price: $73.00 plus tax (Refund Policy)

Abstract:

Currently, the only treatment approved by the US Food and Drug Administration for the treatment of acute stroke is the intravenous recombinant tissue plasminogen activator, which must be administered within a 3 h window. The majority of ischemic stroke patients do not receive intravenous thrombolysis, primarily because they enter the healthcare system too late. Alternative treatment strategies being used or investigated include intra-arterial thrombolysis, endovascular clot disruption, and manipulation and angioplasty with or without stenting. The most promising new revascularization technologies beyond conventional thrombolysis for acute ischemic stroke are ultrasound-enhanced thrombolysis, mechanical clot extraction devices and stent angioplasty. Advances in neuroimaging may allow physicians to determine the etiology of a stroke and tailor treatment accordingly for the maximal clinical benefit for affected patients.

Keywords: acute revascularization; ischemic stroke; thrombectomy; thrombolysis

Document Type: Research article

DOI: http://dx.doi.org/10.2217/14796708.1.1.107

Publication date: 2006-01-01

More about this publication?

Future Neurology provides a forum to address the most important challenges and advances in our understanding of neurological disease, and highlights emerging trends and prospects for effective treatments in common but very serious disorders such as stroke, epilepsy, multiple sclerosis and Parkinson's disease.
Editorial Board
Information for Authors
Submit a Paper
Subscribe to this Title
Information for Advertisers
Terms & Conditions
Information for Librarians
E-Access Trials
ingentaconnect is not responsible for the content or availability of external websites