Author: Dwolatzky, Tzvi

Source: Aging Health, Volume 6, Number 3, June 2010 , pp. 285-287(3)

Publisher: Future Medicine

Abstract:

<bold>Evaluation of: Li NC, Lee A, Whitmer RA et al.: Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis. BMJ 340, B5465 (2010).</bold> A large observational study with a relatively long period of follow-up was designed to evaluate whether angiotensin receptor blockers are associated with protection against Alzheimer's disease or dementia. In the almost entirely male study population (mean age: 74 years) with cardiovascular disease, the use of angiotensin receptor blockers was associated with a reduced incidence of Alzheimer's disease and dementia. For patients with these conditions, the use of angiotensin receptor blockers reduced both mortality and the rate of admission to a nursing home. While these results are of great interest, they should be interpreted with great caution, since the findings refer to a rather specific study population and, thus, lack generalizability. Further research involving more heterogeneous samples is necessary.

Keywords: Alzheimer's disease; angiotensin receptor blocker; cognition; dementia; elderly

Document Type: Research article

DOI: http://dx.doi.org/10.2217/ahe.10.23

Affiliations: 1: †Department of Geriatrics & Memory Clinic, Mental Health Center, PO Box 4600, Beersheva 84170, Israel., Email: tzvidov@bgu.ac.il

Publication date: 2010-06-01

More about this publication?

• Aging Health leading coverage of current and emerging topics relating to the safe and effective management of therapy in the elderly, all subject to rigorous peer review. The journal focuses on the most important advances and highlights their relevance in the clinical setting. The journal has been designed to deliver essential concise information in an easily assimilable format - vital for the increasingly time-constrained professional.
• Editorial Board
• Information for Authors
• Submit a Paper
• Subscribe to this Title
• Information for Advertisers
• Terms & Conditions
• Information for Librarians
• E-Access Trials
• ingentaconnect is not responsible for the content or availability of external websites

Related content

• In this: publication
• By this: publisher
• In this Subject: Medicine (General) ,  Nursing
• By this author: Dwolatzky, Tzvi

Website © Publishing Technology. Article copyright remains with the publisher, society or author(s) as specified within the article.

• Terms and conditions
• Privacy policy
• Information for advertisers