Author: Wang, Jie Jin

Source: Aging Health, Volume 4, Number 6, December 2008 , pp. 597-602(6)

Publisher: Future Medicine

Abstract:

<bold>Evaluation of: Ho L, Boekhoorn SS, Liana L et al.: Cataract surgery and the risk of aging macula disorder: the Rotterdam Study. Invest. Ophthalmol. Vis. Sci. (2008) (Epub ahead of print).</bold> Cataract surgery is among the most frequently performed surgical procedures. Consistent evidence from many population-based studies suggests that cataract surgery may accelerate progression from the early stage of age-related macular degeneration (AMD) to the late stage, resulting in blindness. Two- to five-fold relative risks of late AMD have been reported in eyes 5 or more years after surgery. However, this association has not been consistently observed in clinicbased patient samples. Compared with a cohort of generally healthy older persons, systemic and ocular comorbidities were considerably more prevalent among cataract surgical patients. These differences could partly explain the inconsistent findings between population- and clinic-based studies on the association between cataract surgery and risk of late AMD. Cataract surgery itself may not lead to higher risk of AMD, but could do so by jointly contributing to high risks of late AMD together with other coexisting AMD risk factors.

Keywords: age-related macular degeneration; cataract surgery; clinic-based; cohort study; population-based

Document Type: Research article

DOI: http://dx.doi.org/10.2217/1745509X.4.6.597

Affiliations: 1: Centre for Vision Research, Department of Ophthalmology & Westmead Millennium Institute, University of Sydney, Sydney, Australia and, Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia., Email: jiejin_wang@wmi.usyd.edu.au

Publication date: 2008-12-01

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