Authors: Kihara, A.; Kasamaki, S.; Kamano, T.; Sakamoto, K.; Tomiki, Y.; Ishibiki, Y.

Source: The Journal of International Medical Research, Volume 34, Number 2, March 2006 , pp. 223-230(8)

Publisher: Field House Publishing

Abstract:

Steroids inhibit primary wound healing and delay the formation of granulation tissue, but it has been controversial whether long-term steroid treatment by itself increases the risk of abdominal wound dehiscence. The aim of this study was to determine whether the preoperative dose and post-operative total dose of steroids influence abdominal wound dehiscence. Of 28 patients who had surgery while receiving long-term steroid treatment, seven had abdominal wound dehiscence and 21 did not have dehiscence. The two groups differed significantly in the post-operative dose of steroids (404.3 ± 147.1 and 135.6 ± 118.7 mg, respectively) and the duration of wound healing (57.3 ± 18.0 and 12.4 ± 3.8 days), but no other differences were found. Abdominal wound dehiscence may be influenced by the post-operative rather than the pre-operative steroid dose.

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Keywords: STEROIDS; LONG-TERM TREATMENT; SURGERY; WOUND DEHISCENCE

Document Type: Research article

Publication date: 2006-03-01

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