Authors: Chlumský, J.; Charvát, J.

Source: The Journal of International Medical Research, Volume 33, Number 5, September 2005 , pp. 555-561(7)

Publisher: Field House Publishing

Abstract:

This study measured carotid artery distensibility, intima-media thickness (IMT) and flow-mediated dilatation (FMD) in patients with ischaemic stroke and evaluated if there was a relationship between these measurements and the presence of atrial fibrillation. Distensibility and IMT were measured in 89 patients with ischaemic stroke using ultrasonography; 44 patients had atrial fibrillation. Distensibility was determined using the Reneman equation. FMD was measured in a second group of 52 patients with ischaemic stroke; 20 patients had atrial fibrillation. Patients with atrial fibrillation had lower IMT values compared with patients without atrial fibrillation (0.67 versus 0.79 mm, respectively). Distensibility increased in patients with atrial fibrillation compared with patients without atrial fibrillation (0.19 versus 0.10 mm/100 mmHg, respectively). Patients with atrial fibrillation had significantly better FMD results than patients without atrial fibrillation (5.7% versus 3.2%, respectively). Measuring distensibility, IMT and FMD might be helpful in differentiating between stroke of embolic and thrombotic aetiology.

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Keywords: STROKE; ATRIAL FIBRILLATION; SINUS RHYTHM; CAROTID ARTERY; BRACHIAL ARTERY REACTIVITY; ENDOTHELIAL DYSFUNCTION; INTIMA-MEDIA THICKNESS; FLOW-MEDIATED DILATATION

Document Type: Research article

Publication date: 2005-09-01

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