Home >> Journal of Medical Entomology, Volume 36, Number 6

A New Mechanism Conferring Unprecedented High Resistance to Chlorpyrifos in Culex pipiens (Diptera: Culicidae)

Authors: Pasteur, Nicole; Marquine, Maïté; Cheikh, Hassen Ben; Bernard, Clotilde; 1 and Denis Bourguet3 ,

Source: Journal of Medical Entomology, Volume 36, Number 6, November 1999 , pp. 794-802(9)

Publisher: Entomological Society of America

Buy & download fulltext article:

OR

Price: $28.00 plus tax (Refund Policy)

Abstract:

The cause of high resistance to chlorpyrifos observed in Tunisian Culex pipiens (L.) was investigated by comparing a Tunisian strain G (>10,000-fold resistance), a French strain T (≈50-fold resistance), and a susceptible reference strain S. Strains G and T had the same level of propoxur resistance (≈1,000-fold) and were homozygous for an autosomal propoxur-insensitive acetylcholinesterase (AChE-1). In G and T strains, as well as in the offspring of different F1s and backcrosses using these F1s and the S strain, the effect of DEF and Pb synergists on chlorpyrifos resistance was low or absent, indicating that increased detoxification by enzymes inhibited by these chemicals had a minor role. Chlorpyrifos resistance in the G strain was caused by a major gene (or group of genes) tightly linked to the Ace-1 gene (coding AChE-1 enzyme). The possibility of allelism between this gene and the Ace-1 R allele present in the T strain was rejected by showing that AChE-1 inhibition by chlorpyrifos-oxon was not different between G and T mosquitoes.
More about this publication?
  • Journal of Medical Entomology is published bimonthly in January, March, May, July, September, and November. The journal publishes reports on all phases of medical entomology and medical acarology, including the systematics and biology of insects, acarines, and other arthropods of public health and veterinary significance.

    The journal is divided into the following sections: Morphology, Systematics, Evolution; Sampling, Distribution, Dispersal; Development, Life History; Population and Community Ecology; Behavior, Chemical Ecology; Population Biology/Genetics; Molecular Biology/Genomics; Neurobiology, Physiology, Biochemistry; Vector Control, Pest Management, Resistance, Repellents; Arthropod/Host Interaction, Immunity; Vector/Pathogen/Host Interaction, Transmission; Vector-Borne Diseases, Surveillance, Prevention; Direct Injury, Myiasis, Forensics; Modeling/GIS, Risk Assessment, Economic Impact. In addition to full-length research articles, the journal publishes interpretive articles in a Forum section, Short Communications, Rapid Communications, and Book Reviews.
  • Editorial Board
  • Submit a Paper
  • Subscribe to this Title
  • Information for Advertisers
  • Visit this journal's homepage
  • ingentaconnect is not responsible for the content or availability of external websites
Related content
Marked list

Tools

Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content

Text size:

A | A | A | A
^ Back to top
Share this item with others: These icons link to social bookmarking sites where readers can share and discover new web pages. print icon Print this page